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Chris Daniels (University of Adelaide, Australia)
Sandra Orgeig (University of Adelaide, Australia)
This
symposium explores the physical and structural challenges that face gas
exchange surfaces in vertebrates and insects, focusing on the
surfactant system.
We begin with the initial activation of the pulmonary surfactant system
in vertebrates during the transition from a liquid-filled to an
air-filled lung and explore the dynamic structure and function
relationships of the vertebrate surfactant components. We then explore
the function of the surfactant system during periods of physiological
stress and the special function of surfactant in airways and the
tubular lung of birds. This leads on to a discussion of the structure
and function of the insect tracheal system and the special challenges
that it faces and finally we pose the question whether the insect
tracheal system requires a pulmonary-type surfactant system.
| John N. Maina University of Witwatersrand South Africa |
Development and evolutionary design of the blood-gas barrier for gas exchange surfaces with emphasis on pulmonary surfactant |
| Fred
Possmayer University of Western Ontario Canada |
Role of pulmonary surfactant in regulating the surface tension of the air-liquid interface of the lung in health and disease |
| Joseph
A.
Zasadzinski University of California Santa Barbara, USA |
The Physics of ARDS and Polymer Inhibition Reversal |
| Stephen
B.
Hall Oregon Health & Science University Portland, USA |
Two solid films related to pulmonary surfactant melt at different temperatures |
| Samuel
Schürch University of Calgary Canada |
Wetting and spreading of surfactant films on solid particles: Influence of size, sharp edges and surface irregularities |
| Jesus
Perez-Gil Universidad Complutense Madrid, Spain |
Structure-activity relations of pulmonary surfactant protein SP-B in surfactant phospholipid interfaces |
| Sandra
Orgeig University of Adelaide Australia |
The surfactant film under thermal stress: Insights to a new paradigm for surfactant composition & function |
| Wolfgang
Bernhard Eberhard Karls University Tübingen, Germany |
The role of surfactant lipids in airways of mammals and birds |
| Stefan
K. Hetz Humboldt University Berlin, Germany |
The challenges of the insect tracheal system: ventilation, water loss and oxygen toxicity |
| Cornelis
Jaco Klok Arizona State University Phoenix, USA |
Physiological constraints of atmospheric oxygen levels on insect body size, tracheal structure and function |
| Samuel Schürch & Stefan Hetz | Is there a role for a pulmonary-type surfactant in the tracheae of insects? A theoretical analysis to serve as an introduction for a discussion forum. |
Related posters:
| Antonio Cruz University of Madrid, Spain |
Characterization of nanoscopic assemblies of pulmonary surfactant proteins in native membranes |
| Barbara Olmeda University of Madrid, Spain |
Effect of hypoxia on the composition and surface activity of pulmonary surfactant |
| Albert Bennett University of California Irvine, USA |
Leptin evolution in diving mammals: A role in surfactant production? |