ICRB 2006 - Deconvoluting Lung Evolution: From Phenotypes to Gene Regulatory Networks

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Program

Lectures and Symposia updated June 12, 2006

Lectures:

Keynote Lecture: Gills, lungs and spiracles - fossil evidence for the evolution of air breathing

Plenary Lecture: Experimental Evolution as an Approach to Study Respiratory Biology

Plenary Lecture: Neuronal and Chemosensory Control of Breathing: Lessons Learned from a Simple Model System Approach

Plenary Lecture:
The Use of Molecular Tools in Integrative Respiratory Physiology

Symposia:

Homeostatic Responses to Changing Metabolic Demands

Developmental Transitions in Respiratory Physiology

Sensing CO₂, H+ and O₂; A Comparative Survey of Receptors and Pathways

The Integrative and Evolutionary Biology of Gas-Binding Proteins

Coping with Cyclic Oxygen Availability: Evolutionary Aspects

Directions in Respiratory Biology

Respiratory Plasticity after Changes in Oxygen Supply and Demand

Radicals and Foreign Airborne Substances

Innovative Methods in Respiratory Biology

Breathing during Locomotion

The Anatomy, Physics and Physiology of Gas Exchange Surfaces with Emphasis on Pulmonary Surfactant

Mitochondria and Respiration

Deconvoluting Lung Evolution: From Phenotypes to Gene Regulatory Networks

Reconfiguration of the Respiratory Network During Respiratory and Non-Respiratory Behaviours

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Deconvoluting Lung Evolution: From Phenotypes to Gene Regulatory Networks
John Torday (University of California, Los Angeles, USA)

The symposium will take the audience from broad consideration of gas exchange unit phenotypes in phylogeny and ontogeny to highly conserved cellular/molecular mechanisms that determine lung morphogenesis. An empiric cell/molecular paracrine mechanism will be presented for alveolar evolution based on selection for specific Gene Regulatory Networks that drive the phylogeny and ontogeny of the gas exchange unit.

Steven F. Perry University of Bonn Germany	Origin and early radiation of vertebrate lungs
James W. Hicks University of California Irvine, USA	Patterns and Processes in the Evolution of the Vertebrate Cardiopulmonary System
John Maina University of the Witwatersrand South Africa	Comparative functional design of the vertebrate lung with particular emphasis on the avian lung
Ewald Weibel University of Bern Switzerland	Lung Design for Efficient Gas Exchange: Lessons from Comparative Physiology and Morphometry
Ralf J. Sommer Max Planck Institute for Developmental Biology Tübingen, Germany	Evolution of nematode vulva development: Drastic changes of signaling networks in a conserved developmental system
John Torday University of California Los Angeles, USA	Deconvoluting Lung Evolution by “Haeckeling” Functional Genomics